Sec8 anticorps (N-Term)

N° du produit ABIN2786600

L’anticorps Lapin Polyclonal anti-Sec8 a été validé pour WB. Il convient pour détecter Sec8 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Lapin, Chien et Poisson zèbre (Danio rerio).

Aperçu rapide pour Sec8 anticorps (N-Term) (ABIN2786600)

Antigène: Sec8 (EXOC4) (Exocyst Complex Component 4 (EXOC4))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Lapin, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sec8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Sec8 anticorps

Épitope: N-Term

Séquence: MAAEAAGGKY RSTVSKSKDP SGLLISVIRT LSTSDDVEDR ENEKGRLEEA

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against EXOC4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human EXOC4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 473 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Sec8

Antigène: Sec8 (EXOC4) (Exocyst Complex Component 4 (EXOC4))

Autre désignation: EXOC4

Sujet: The specific function of this protein remains unknown.The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: MGC27170, REC8, SEC8, SEC8L1, Sec8p
Protein Interaction Partner: SUMO2, UBC, EXOC2, EXOC7, ATG5, ATG12, BECN1, EXOC8, EGFR, EXOC1, EXOC3, nef, IQCB1, EXOC5, UBD, MYO5A, DTNBP1, CEP63, DISC1, Poc1b, GTF2E2, DLGAP4, DLG3, RALA, GRIN2B, DLG4, MYC,
Protein Size: 473

Poids moléculaire: 54 kDa

ID gène: 60412

NCBI Accession: NM_001037126, NP_001032203

UniProt: Q8TAR2

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis