PSMB3 anticorps (Middle Region)

N° du produit ABIN2786717

L’anticorps Lapin Polyclonal anti-PSMB3 a été validé pour WB. Il convient pour détecter PSMB3 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Poisson zèbre (Danio rerio), Chévre, Cobaye et Saccharomyces cerevisiae. Il y a 1 publication disponible.

Aperçu rapide pour PSMB3 anticorps (Middle Region) (ABIN2786717)

Antigène: PSMB3 (Proteasome Subunit beta 3 (PSMB3))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Poisson zèbre (Danio rerio), Chévre, Cobaye, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMB3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PSMB3 anticorps

Épitope: Middle Region

Séquence: LNLYELKEGR QIKPYTLMSM VANLLYEKRF GPYYTEPVIA GLDPKTFKPF

Homologie: Cow: 100%, Dog: 100%, Goat: 91%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against PSMB3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PSMB3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 205 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PSMB3 (ABIN2786717)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Détails sur PSMB3

Antigène: PSMB3 (Proteasome Subunit beta 3 (PSMB3))

Autre désignation: PSMB3

Sujet: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Pseudogenes have been identified on chromosomes 2 and 12.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Pseudogenes have been identified on chromosomes 2 and 12. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HC10-II, MGC4147
Protein Interaction Partner: UBC, TRIM27, PSMD14, PSMG3, POMP, AP3M1, PSME4, SART3, PSMB7, PSMB6, PSMB5, PSMB4, PSMB2, PSMB1, PSMA7, PSMA6, PSMA5, PSMA4, PYCRL, PSMA3, PSMA1, KIF5B, EPB41L1, CAST, HECW2, TP53, PSMA2, PARK2, BAG3, MPZ, PRMT2, FN1, CFTR, IQCB1, PSMD13, PSMD12, PSMD11,
Protein Size: 205

Poids moléculaire: 23 kDa

ID gène: 5691

NCBI Accession: NM_002795, NP_002786

UniProt: P49720

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Cell RedoxHomeostasis, Lipid Metabolism