PSMB3 anticorps (Middle Region)

N° du produit ABIN2786717

Détail du produit anti-PSMB3 anticorps

Antigène: PSMB3 (Proteasome Subunit beta 3 (PSMB3))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Poisson zèbre (Danio rerio), Chévre, Cobaye, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMB3 est non-conjugé

Application: Western Blotting (WB)

Séquence: LNLYELKEGR QIKPYTLMSM VANLLYEKRF GPYYTEPVIA GLDPKTFKPF

Homologie: Cow: 100%, Dog: 100%, Goat: 91%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against PSMB3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PSMB3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 205 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PSMB3 (ABIN2786717)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Détails sur PSMB3

Antigène: PSMB3 (Proteasome Subunit beta 3 (PSMB3))

Autre désignation: PSMB3 (PSMB3 Produits)

Synonymes: anticorps HC10-II, anticorps AL033320, anticorps C10-II, anticorps PSB3, anticorps psmb3, anticorps wu:fb11d10, anticorps wu:fu88b08, anticorps zgc:56374, anticorps DDBDRAFT_0190542, anticorps DDBDRAFT_0232932, anticorps DDB_0190542, anticorps DDB_0232932, anticorps proteasome subunit beta 3, anticorps proteasome (prosome, macropain) subunit, beta type 3, anticorps proteasome subunit C10-11, anticorps proteasome subunit beta type-3, anticorps proteasome subunit beta 3 S homeolog, anticorps 20S proteasome subunit beta-3, anticorps PSMB3, anticorps Psmb3, anticorps LOC100135869, anticorps LOC399377, anticorps psmb3.S, anticorps psmb3, anticorps psmB3

Sujet: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Pseudogenes have been identified on chromosomes 2 and 12.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Pseudogenes have been identified on chromosomes 2 and 12. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HC10-II, MGC4147
Protein Interaction Partner: UBC, TRIM27, PSMD14, PSMG3, POMP, AP3M1, PSME4, SART3, PSMB7, PSMB6, PSMB5, PSMB4, PSMB2, PSMB1, PSMA7, PSMA6, PSMA5, PSMA4, PYCRL, PSMA3, PSMA1, KIF5B, EPB41L1, CAST, HECW2, TP53, PSMA2, PARK2, BAG3, MPZ, PRMT2, FN1, CFTR, IQCB1, PSMD13, PSMD12, PSMD11,
Protein Size: 205

Poids moléculaire: 23 kDa

ID gène: 5691

NCBI Accession: NM_002795, NP_002786

UniProt: P49720

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Cell RedoxHomeostasis, Lipid Metabolism