SH3BP2 anticorps (Middle Region)
-
- Antigène Voir toutes SH3BP2 Anticorps
- SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
-
Épitope
- Middle Region
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp SH3BP2 est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- RQPSQADTGG DDSDEDYEKV PLPNSVFVNT TESCEVERLF KATSPRGEPQ
- Homologie
- Cow: 85%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against SH3BP2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human SH3BP2
- Top Product
- Discover our top product SH3BP2 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 561 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
- Autre désignation
- SH3BP2 (SH3BP2 Produits)
- Sujet
-
SH3BP2 has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism.
Alias Symbols: 3BP2, CRBM, CRPM, FLJ42079, RES4-23, 3BP-2
Protein Interaction Partner: RNF146, TNKS2, PDLIM7, TNKS, UBC, ERBB2, VAV1, SYK, SRC, CBL, SH3KBP1, DBNL, VAV3, LAT, VAV2, PLCG2, TF, ABL1, ZAP70, PLCG1, LCK, YWHAQ, FYN, FLT3, FGFR1, GRB2,
Protein Size: 561 - Poids moléculaire
- 62 kDa
- ID gène
- 6452
- NCBI Accession
- NM_003023, NP_003014
- UniProt
- P78314
- Pathways
- TCR Signaling
-