Retinoblastoma Binding Protein 4 anticorps (C-Term)

N° du produit ABIN2786818

Cet anticorps anti-Retinoblastoma Binding Protein 4 Polyclonal Lapin (ABIN2786818) détecte spécifiquement Retinoblastoma Binding Protein 4 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin et Chien.

Aperçu rapide pour Retinoblastoma Binding Protein 4 anticorps (C-Term) (ABIN2786818)

Antigène: Retinoblastoma Binding Protein 4 (RBBP4)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Retinoblastoma Binding Protein 4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Retinoblastoma Binding Protein 4 anticorps

Épitope: C-Term

Fonction: Rbbp4 Antibody - C-terminal region

Séquence: TAKISDFSWN PNEPWVICSV SEDNIMQVWQ MAENIYNDED PEGSVDPEGQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Rbbp4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Rbbp4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56649-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Retinoblastoma Binding Protein 4

Antigène: Retinoblastoma Binding Protein 4 (RBBP4)

Autre désignation: Rbbp4

Sujet:

Background Information: Rbbp4 is a core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair, the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression, the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling, and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development, and the NURF (nucleosome remodeling factor) complex.

Gene Name: retinoblastoma binding protein 4

Alternative Symbols: RBA, RBAP48, mRbAp48

Protein Name: Histone-binding protein RBBP4

Poids moléculaire: 47kDa

ID gène: 19646

NCBI Accession: NP_033056

UniProt: Q60972

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, Stem Cell Maintenance, Chromatin Binding, Protein targeting to Nucleus