PRR5 anticorps (C-Term)
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- Antigène Voir toutes PRR5 Anticorps
- PRR5 (Proline Rich 5 (Renal) (PRR5))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PRR5 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- SPAPHSGPCP SRLYPTTQPP EQGLDPTRSS LPRSSPENLV DQILESVDSD
- Homologie
- Cow: 100%, Dog: 91%, Horse: 86%, Human: 100%, Pig: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against PRR5. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human PRR5
- Top Product
- Discover our top product PRR5 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 379 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PRR5 (Proline Rich 5 (Renal) (PRR5))
- Autre désignation
- PRR5 (PRR5 Produits)
- Synonymes
- anticorps AU043908, anticorps Arhgap8, anticorps C030017C09Rik, anticorps C78947, anticorps Protor-1, anticorps Protor1, anticorps FLJ20185k, anticorps PP610, anticorps PROTOR-1, anticorps PROTOR1, anticorps pp610, anticorps protor1, anticorps protor2, anticorps proline rich 5 (renal), anticorps proline rich 5, anticorps proline rich 5 L homeolog, anticorps Prr5, anticorps PRR5, anticorps prr5.L
- Sujet
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This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.
Alias Symbols: PP610, PROTOR1, PROTOR-1, FLJ20185k,
Protein Interaction Partner: MTOR, BRCA1, UBC, RICTOR, MAPKAP1, MLST8,
Protein Size: 293 - Poids moléculaire
- 32 kDa
- ID gène
- 55615
- NCBI Accession
- NM_001017528, NP_056181
- Pathways
- Signalisation PI3K-Akt
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