TBC1D7 anticorps (C-Term)

N° du produit ABIN2786978

Cet anticorps Lapin Polyclonal détecte spécifiquement TBC1D7 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Chévre, Cobaye, Cheval, Lapin et Porc.

Aperçu rapide pour TBC1D7 anticorps (C-Term) (ABIN2786978)

Antigène: TBC1D7 (TBC1 Domain Family, Member 7 (TBC1D7))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Chévre, Cobaye, Cheval, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TBC1D7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TBC1D7 anticorps

Épitope: C-Term

Séquence: ISRCFVKQLN NKYRDALPQL PKAFEQYLNL EDSRLLSHLK TCSAVSKLPY

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against Tbc1d7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Tbc1d7

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 293 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TBC1D7

Antigène: TBC1D7 (TBC1 Domain Family, Member 7 (TBC1D7))

Autre désignation: Tbc1d7

Sujet: Tbc1d7 is a component of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward RHEB in response to alterations in specific cellular growth conditions. The small GTPase RHEB is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB. Participates in the proper sensing of growth factors and glucose, but not amino acids, by mTORC1. It is unclear whether TBC1D7 acts as a GTPase-activating protein and additional studies are required to answer this question.
Alias Symbols: 2610009C09Rik
Protein Interaction Partner: Ywhae,
Protein Size: 293

Poids moléculaire: 32 kDa

ID gène: 67046

NCBI Accession: NM_025935, NP_080211

UniProt: Q9D0K0