PINX1 anticorps (Middle Region)
Aperçu rapide pour PINX1 anticorps (Middle Region) (ABIN2787041)
Antigène
Voir toutes PINX1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- EKKSFSLEEK SKISKNRVHY MKFTKGKDLS SRSKTDLDCI FGKRQSKKTP
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against PINX1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human PINX1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 328 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
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Autre désignation
- PINX1
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Sujet
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PINX1 is a microtubule-binding protein essential for faithful chromosome segregation. PINX1 mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. PINX1 inhibits telomerase activity and may inhibit cell proliferation and act as tumor suppressor.
Alias Symbols: FLJ20565, LPTL, LPTS, MGC8850
Protein Interaction Partner: UBC, CACYBP, TP63, GABPA, TERF1, DHX15, AIDA, MCRS1, PAFAH1B2, TERT, MPZ, HRNR, PLEKHJ1, PABPC1, GTPBP4, PABPC4, TXN, RPS28, RPS19, RPS16, RPS10, RPS3A, RPL31, RPL23A, CAPRIN1, CALM3, AHCY,
Protein Size: 328 -
Poids moléculaire
- 37 kDa
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ID gène
- 54984
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NCBI Accession
- NM_017884, NP_060354
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UniProt
- Q96BK5
Antigène
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