CHMP1B anticorps (N-Term)

N° du produit ABIN2787213

L’anticorps Lapin Polyclonal anti-CHMP1B a été validé pour WB. Il convient pour détecter CHMP1B dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cheval, Poisson zèbre (Danio rerio) et Cobaye.

Aperçu rapide pour CHMP1B anticorps (N-Term) (ABIN2787213)

Antigène: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHMP1B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CHMP1B anticorps

Épitope: N-Term

Séquence: KIKKAIQKGN MEVARIHAEN AIRQKNQAVN FLRMSARVDA VAARVQTAVT

Homologie: Cow: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CHMP1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CHMP1B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 199 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CHMP1B

Antigène: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Autre désignation: CHMP1B

Sujet: CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
Alias Symbols: C10orf2, C18-ORF2, C18orf2, CHMP1.5, Vps46-2, Vps46B, hVps46-2
Protein Interaction Partner: STAMBP, UBC, ATP6V1B1, CHMP4B, KNSTRN, CHMP1B, CHMP5, VPS4A, CNOT10, SNRNP200, SUCLG1, RAB11A, RASSF7, SSRP1, CHMP1A, USP54, USP8, SPAST, ELAVL1, IST1, VPS4B,
Protein Size: 199

Poids moléculaire: 22 kDa

ID gène: 57132

NCBI Accession: NM_020412, NP_065145

UniProt: Q7LBR1