CHMP1B anticorps (N-Term)

N° du produit ABIN2787213

L’anticorps anti-CHMP1B Polyclonal Lapin est utilisé pour la détection de CHMP1B dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cheval, Poisson zèbre (Danio rerio) et Cobaye. Il a été validé pour WB.

Aperçu rapide pour CHMP1B anticorps (N-Term) (ABIN2787213)

Antigène: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHMP1B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CHMP1B anticorps

Épitope: N-Term

Fonction: CHMP1B Antibody - N-terminal region

Séquence: KIKKAIQKGN MEVARIHAEN AIRQKNQAVN FLRMSARVDA VAARVQTAVT

Homologie: Cow: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CHMP1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CHMP1B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57408-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CHMP1B

Antigène: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Autre désignation: CHMP1B

Sujet:

Background Information: CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).

Gene Name: Charged multivesicular body protein 1B

Alternative Symbols: Vps46B, C10orf2, C18orf2, CHMP1.5, Vps46-2, C18-ORF2, hVps46-2

Protein Name: Charged multivesicular body protein 1b

Poids moléculaire: 22kDa

ID gène: 57132

NCBI Accession: NP_065145

UniProt: Q7LBR1