TRIB3 anticorps (N-Term)

N° du produit ABIN2787258

Cet anticorps Lapin Polyclonal détecte spécifiquement TRIB3 dans WB. Il présente une réactivité avec des échantillons de Humain, Boeuf (Vache), Mouton et Porc.

Aperçu rapide pour TRIB3 anticorps (N-Term) (ABIN2787258)

Antigène: TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

Reactivité: Humain, Boeuf (Vache), Mouton, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIB3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TRIB3 anticorps

Épitope: N-Term

Séquence: KNNRMSANND HFLTPTWQQM RATPLAAPAG SLSRKKRLEL DDNLDTERPV

Homologie: Cow: 91%, Human: 100%, Pig: 91%, Sheep: 91%

Attributs du produit: This is a rabbit polyclonal antibody against TRIB3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of human TRIB3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TRIB3

Antigène: TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

Autre désignation: TRIB3

Sujet: The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants.
Alias Symbols: NIPK, SINK, TRB3, SKIP3, C20orf97
Protein Size: 385

Poids moléculaire: 42 kDa

ID gène: 57761

NCBI Accession: NM_001301201, NP_001288130

UniProt: J3KR25

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha