TRIB3 anticorps (N-Term)

N° du produit ABIN2787259

L’anticorps Lapin Polyclonal anti-TRIB3 a été validé pour WB. Il convient pour détecter TRIB3 dans des échantillons de Humain, Rat, Boeuf (Vache), Mouton, Cobaye, Lapin et Chien.

Aperçu rapide pour TRIB3 anticorps (N-Term) (ABIN2787259)

Antigène: TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

Reactivité: Humain, Rat, Boeuf (Vache), Mouton, Cobaye, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIB3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TRIB3 anticorps

Épitope: N-Term

Séquence: YVLLEPEEGG RAYQALHCPT GTEYTCKVYP VQEALAVLEP YARLPPHKHV

Homologie: Cow: 79%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Rabbit: 86%, Rat: 79%, Sheep: 79%

Attributs du produit: This is a rabbit polyclonal antibody against TRIB3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TRIB3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 358 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TRIB3

Antigène: TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

Autre désignation: TRIB3

Sujet: The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1.
Alias Symbols: C20orf97, NIPK, SINK, SKIP3, TRB3
Protein Interaction Partner: RPGRIP1, UBC, DDIT3, ATF4, RFWD2, PRMT5, AKT1, APP, SMURF1, CDC25A, BMPR2, SMAD3, BCL6, COPS6, RBM48, EEF1G, SETDB1, GIT1, GDF9, KAT5, AKT2, RELA, ATF5, HRSP12, TIAF1, MCM3AP, LTBP4, SIAH1, RBM4, PSMA3, RPSA, HLA-B, GRN, FN1, CSNK2B,
Protein Size: 358

Poids moléculaire: 39 kDa

ID gène: 57761

NCBI Accession: NM_021158, NP_066981

UniProt: Q96RU7

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha