GREM2 anticorps (N-Term)

N° du produit ABIN2787313

Cet anticorps Lapin Polyclonal détecte spécifiquement GREM2 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Cobaye, Chien et Cheval.

Aperçu rapide pour GREM2 anticorps (N-Term) (ABIN2787313)

Antigène: GREM2 (Gremlin 2 (GREM2))

Reactivité: Humain, Souris, Rat, Cobaye, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GREM2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GREM2 anticorps

Épitope: N-Term

Séquence: MFWKLSLSLF LVAVLVKVAE ARKNRPAGAI PSPYKDGSSN NSERWQHQIK

Homologie: Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against GREM2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GREM2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 168 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GREM2

Antigène: GREM2 (Gremlin 2 (GREM2))

Autre désignation: GREM2

Sujet: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.
Alias Symbols: CKTSF1B2, DAND3, PRDC
Protein Interaction Partner: BMP4, BMP2,
Protein Size: 168

Poids moléculaire: 17 kDa

ID gène: 64388

NCBI Accession: NM_022469, NP_071914

UniProt: Q9H772