SMEK1 anticorps (Middle Region)

N° du produit ABIN2787340

Cet anticorps Lapin Polyclonal détecte spécifiquement SMEK1 dans WB. Il présente une réactivité envers Souris, Humain, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval et Lapin.

Aperçu rapide pour SMEK1 anticorps (Middle Region) (ABIN2787340)

Antigène: SMEK1 (Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1))

Reactivité: Souris, Humain, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMEK1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SMEK1 anticorps

Épitope: Middle Region

Séquence: YWKALEDVDY VQTFKGLKLR FEQQRERQDN PKLDSMRSIL RNHRYRRDAR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SMEK1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SMEK1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 820 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SMEK1

Antigène: SMEK1 (Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1))

Autre désignation: SMEK1

Sujet: SMEK1 is the regulatory subunit of serine/threonine-protein phosphatase 4.SMEK1 may regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
Alias Symbols: FLFL1, KIAA2010, MSTP033, smk-1, smk1, PP4R3A
Protein Interaction Partner: HUWE1, UBC, PPP4R2, BRCC3, SF3A1, HNRNPR, TELO2, MTA2, PSMB1, PSMA2, DDB2, CAST, ARCN1, AMPD2, ACACA, CASK, POLR2A, IGBP1, PPP4C, HDAC1, MAPK14,
Protein Size: 820

Poids moléculaire: 94 kDa

ID gène: 55671

NCBI Accession: NM_032560, NP_115949

Pathways: Regulation of Carbohydrate Metabolic Process