BBS4 anticorps (N-Term)

N° du produit ABIN2787344

Cet anticorps Lapin Polyclonal détecte spécifiquement BBS4 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Porc, Lapin, Poisson zèbre (Danio rerio) et Cobaye.

Aperçu rapide pour BBS4 anticorps (N-Term) (ABIN2787344)

Antigène: BBS4 (Bardet-Biedl Syndrome 4 (BBS4))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Porc, Lapin, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BBS4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BBS4 anticorps

Épitope: N-Term

Séquence: YVQALIFRLE GNIQESLELF QTCAVLSPQS ADNLKQVARS LFLLGKHKAA

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against BBS4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human BBS4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 519 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur BBS4

Antigène: BBS4 (Bardet-Biedl Syndrome 4 (BBS4))

Autre désignation: BBS4

Sujet: This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein "BBSome" complex with six other BBS proteins. Alternative splice variants have been described but their predicted protein products have not been experimentally verified.
Alias Symbols: -
Protein Interaction Partner: MYOG, HSCB, FHOD1, EXOC7, EIF3A, PCM1, PAX2, KRT18, EPAS1, EEF1A1, DCTN1, CALCA, BHMT, ALDOB, ACTB, CUL3, UBC,
Protein Size: 519

Poids moléculaire: 58 kDa

ID gène: 585

NCBI Accession: NM_033028, NP_149017

UniProt: Q96RK4

Pathways: Signalisation Hedgehog, Tube Formation, Maintenance of Protein Location