OPA1 anticorps (N-Term)

N° du produit ABIN2787355

Cet anticorps anti-OPA1 est un anticorps Lapin Polyclonal détectant OPA1 dans WB. Adapté pour Humain, Rat, Souris, Lapin, Chien, Boeuf (Vache), Cobaye, Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour OPA1 anticorps (N-Term) (ABIN2787355)

Antigène: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Reactivité: Humain, Rat, Souris, Lapin, Chien, Boeuf (Vache), Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OPA1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-OPA1 anticorps

Épitope: N-Term

Séquence: SPEETAFRAT DRGSESDKHF RKVSDKEKID QLQEELLHTQ LKYQRILERL

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against OPA1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 924 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur OPA1

Antigène: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Autre désignation: OPA1

Sujet: This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ12460, KIAA0567, MGM1, NPG, NTG, largeG
Protein Interaction Partner: UBC, PARK2, MYC, HSP90AA5P, NIT2, HTRA2, NPTX1, NDUFS8, NDUFS1, NDUFA9, ILF3, HADHB, ECH1, DNASE2, APP, SMAD3, SMAD2, CAND1, CUL3, ELAVL1, MME,
Protein Size: 924

Poids moléculaire: 102 kDa

ID gène: 4976

NCBI Accession: NM_130831, NP_570844

UniProt: E5KLK2

Pathways: Tube Formation