RAD1 anticorps (Middle Region)
Aperçu rapide pour RAD1 anticorps (Middle Region) (ABIN2787356)
Antigène
Voir toutes RAD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- ITMSPDKPYF RLSTFGNAGS SHLDYPKDSD LMEAFHCNQT QVNRYKISLL
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against RAD1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human RAD1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 282 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RAD1 (Cell Cycle Checkpoint Protein RAD1 (RAD1))
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Autre désignation
- RAD1
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Sujet
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This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described.
Alias Symbols: HRAD1, REC1
Protein Interaction Partner: ATRX, FEN1, UBC, MSH3, MSH2, MSH6, COPS5, HUS1, ATR, MAP1LC3B, HUS1B, RAD9B, RAD17, POLB, DNAJC7, PARK2, RPA2, RPA1, RAD9A,
Protein Size: 282 -
Poids moléculaire
- 32 kDa
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ID gène
- 5810
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NCBI Accession
- NM_002853, NP_002844
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UniProt
- O60671
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Pathways
- M Phase
Antigène
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