Kallikrein 7 anticorps (Middle Region)

N° du produit ABIN2787364

Détail du produit anti-Kallikrein 7 anticorps

Antigène: Kallikrein 7 (KLK7)

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Porc, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 7 est non-conjugé

Application: Western Blotting (WB)

Séquence: IKASKSFRHP GYSTQTHVND LMLVKLNSQA RLSSMVKKVR LPSRCEPPGT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 86%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against KLK7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human KLK7

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Kallikrein 7

Antigène: Kallikrein 7 (KLK7)

Autre désignation: KLK7 (KLK7 Produits)

Synonymes: anticorps Prss6, anticorps SCCE, anticorps PRSS6, anticorps hK7, anticorps kallikrein related-peptidase 7 (chymotryptic, stratum corneum), anticorps kallikrein-related peptidase 7, anticorps kallikrein related peptidase 7, anticorps Klk7, anticorps KLK7

Sujet: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis.
Protein Interaction Partner: APP, UBC, CDSN,
Protein Size: 181

Poids moléculaire: 19 kDa

ID gène: 5650

Pathways: Système du Complément