Kallikrein 7 anticorps (Middle Region)
Aperçu rapide pour Kallikrein 7 anticorps (Middle Region) (ABIN2787364)
Antigène
Voir toutes Kallikrein 7 (KLK7) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- KLK7 Antibody - middle region
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Séquence
- IKASKSFRHP GYSTQTHVND LMLVKLNSQA RLSSMVKKVR LPSRCEPPGT
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 86%, Rat: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against KLK7. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Human KLK7
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57735-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Kallikrein 7 (KLK7)
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Autre désignation
- KLK7
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Sujet
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Background Information: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis.
Gene Name: kallikrein-related peptidase 7
Alternative Symbols: hK7, SCCE, PRSS6
Protein Name: Kallikrein-7
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Poids moléculaire
- 19kDa
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ID gène
- 5650
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UniProt
- P49862
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Pathways
- Système du Complément
Antigène
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