ATG4B anticorps (N-Term)

N° du produit ABIN2787433

L’anticorps anti-ATG4B Polyclonal Lapin est utilisé pour la détection de ATG4B dans des échantillons de Humain, Souris, Rat, Chien, Cobaye, Lapin et Boeuf (Vache). Il a été validé pour WB et IHC.

Aperçu rapide pour ATG4B anticorps (N-Term) (ABIN2787433)

Antigène: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Lapin, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG4B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ATG4B anticorps

Épitope: N-Term

Fonction: ATG4B Antibody - N-terminal region

Séquence: WGCMLRCGQM IFAQALVCRH LGRDWRWTQR KRQPDSYFSV LNAFIDRKDS

Homologie: Cow: 92%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 85%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ATG4B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ATG4B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57862-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur ATG4B

Antigène: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Autre désignation: ATG4B

Sujet:

Background Information: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. ATG4B is a member of the autophagin protein family, it is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Name: ATG4 autophagy related 4 homolog B (S. cerevisiae)

Alternative Symbols: APG4B, AUTL1

Protein Name: Cysteine protease ATG4B

Poids moléculaire: 44kDa

ID gène: 23192

NCBI Accession: NP_037457

UniProt: Q9Y4P1

Pathways: Autophagy