MED7 anticorps (Middle Region)

N° du produit ABIN2787458

Détail du produit anti-MED7 anticorps

Antigène: MED7 (Mediator Complex Subunit 7 (MED7))

Épitope: Middle Region

Reactivité: Humain, Souris, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval, Rat, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED7 est non-conjugé

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Séquence: KRQRLETAER FQKHLERVIE MIQNCLASLP DDLPHSEAGM RVKTEPMDAD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MED7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MED7

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 233 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MED7

Antigène: MED7 (Mediator Complex Subunit 7 (MED7))

Autre désignation: MED7 (MED7 Produits)

Sujet: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: CRSP33, CRSP9, MGC12284, ARC34
Protein Interaction Partner: HAUS1, CDK8, CDK19, MED13, MED19, MED26, EPAS1, MED6, UBE2I, UL48, SUMO2, UBC, CTDP1, MED10, MED25, MED15, MED14, VDR, SREBF1, RELA, PARP1, ZSCAN1, TRIM15, RHOXF2, PCBD2, MED31, TRIM29, RBFOX2, IKBKG, LZTR1, PML, MED9, MED8, HGS, MED1, HNF4A, ESR2, ESR1,
Protein Size: 233

Poids moléculaire: 27 kDa

ID gène: 9443

NCBI Accession: NM_004270, NP_004261

UniProt: O43513

Pathways: Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha