KDM2A anticorps (Middle Region)

N° du produit ABIN2787493

Détail du produit anti-KDM2A anticorps

Antigène: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Porc, Lapin, Boeuf (Vache), Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM2A est non-conjugé

Application: Western Blotting (WB)

Séquence: LTPPADKPGQ DNRSKLRNMT DFRLAGLDIT DATLRLIIRH MPLLSRLDLS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against KDM2A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human KDM2A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KDM2A

Antigène: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Autre désignation: KDM2A (KDM2A Produits)

Synonymes: anticorps FBXL11, anticorps JHDM1A, anticorps 100043628, anticorps 5530401A10Rik, anticorps AA589516, anticorps AW536790, anticorps Cxxc8, anticorps Fbl11, anticorps Fbl7, anticorps Fbxl11, anticorps Gm4560, anticorps Jhdm1, anticorps Jhdm1a, anticorps lalina, anticorps KDM2A, anticorps CXXC8, anticorps FBL11, anticorps FBL7, anticorps LILINA, anticorps fb76b11, anticorps wu:fb76b11, anticorps wu:fj11c04, anticorps zgc:158441, anticorps zgc:158606, anticorps lysine demethylase 2A, anticorps lysine (K)-specific demethylase 2A, anticorps lysine (K)-specific demethylase 2Aa, anticorps KDM2A, anticorps Kdm2a, anticorps kdm2aa

Sujet: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3.
Alias Symbols: CXXC8, FBL11, FBL7, FBXL11, JHDM1A, LILINA
Protein Interaction Partner: RB1, E2F1, EED, SKP1, MPG, ZNF512B, UBE2G2, SMAD7, SMAD3, HIST3H3, HIST2H3C, KIAA0368, ELAVL1, UBC, BCL6, FOS, RELA,
Protein Size: 620

Poids moléculaire: 68 kDa

ID gène: 22992

NCBI Accession: NM_012308, NP_036440

Pathways: L'effet Warburg