Metabotropic Glutamate Receptor 6 anticorps (N-Term)

N° du produit ABIN2787505

L’anticorps Lapin Polyclonal anti-Metabotropic Glutamate Receptor 6 a été validé pour WB. Il convient pour détecter Metabotropic Glutamate Receptor 6 dans des échantillons de Humain, Rat, Souris, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval, Poisson zèbre (Danio rerio), Porc et Mouton.

Aperçu rapide pour Metabotropic Glutamate Receptor 6 anticorps (N-Term) (ABIN2787505)

Antigène: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Reactivité: Humain, Rat, Souris, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval, Poisson zèbre (Danio rerio), Porc, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Metabotropic Glutamate Receptor 6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Metabotropic Glutamate Receptor 6 anticorps

Épitope: N-Term

Séquence: AGGLTLGGLF PVHARGAAGR ACGQLKKEQG VHRLEAMLYA LDRVNADPEL

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 93%, Sheep: 79%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against GRM6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GRM6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 877 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Metabotropic Glutamate Receptor 6

Antigène: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Autre désignation: GRM6

Sujet: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Alias Symbols: CSNB1B, DKFZp686H1993, GPRC1F, MGLUR6, mGlu6
Protein Interaction Partner: GNAO1,
Protein Size: 877

Poids moléculaire: 95 kDa

ID gène: 2916

NCBI Accession: NM_000843, NP_000834

UniProt: O15303