MED14 anticorps (Middle Region)

N° du produit ABIN2787568

Cet anticorps anti-MED14 Polyclonal Lapin (ABIN2787568) détecte spécifiquement MED14 dans WB et ChIP. L’anticorps est réactif avec des échantillons de Humain, Souris et Lapin.

Aperçu rapide pour MED14 anticorps (Middle Region) (ABIN2787568)

Antigène: MED14 (Mediator Complex Subunit 14 (MED14))

Reactivité: Humain, Souris, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED14 est non-conjugé

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Détail du produit anti-MED14 anticorps

Épitope: Middle Region

Fonction: MED14 Antibody - middle region

Séquence: AADREDSPAM ALLLQQFKEN IQDLVFRTKT GKQTRTNAKR KLSDDPCPVE

Homologie: Human: 100%, Mouse: 79%, Rabbit: 86%

Attributs du produit: This is a rabbit polyclonal antibody against MED14. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MED14

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58139-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur MED14

Antigène: MED14 (Mediator Complex Subunit 14 (MED14))

Autre désignation: MED14

Sujet:

Targeted Subunit: 14

Background Information: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.

Gene Name: Mediator complex subunit 14

Alternative Symbols: CSRP, RGR1, CRSP2, EXLM1, CXorf4, CRSP150, DRIP150, TRAP170

Protein Name: Mediator of RNA polymerase II transcription subunit 14

Poids moléculaire: 161 kDa

ID gène: 9282

NCBI Accession: NP_004220

UniProt: O60244

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha