HMGB2 anticorps (Middle Region)

N° du produit ABIN2787574

L’anticorps Lapin Polyclonal anti-HMGB2 a été validé pour WB et IHC. Il convient pour détecter HMGB2 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye, Porc et Poisson zèbre (Danio rerio).

Aperçu rapide pour HMGB2 anticorps (Middle Region) (ABIN2787574)

Antigène: HMGB2 (High Mobility Group Box 2 (HMGB2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye, Porc, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMGB2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-HMGB2 anticorps

Épitope: Middle Region

Séquence: DREMKNYVPP KGDKKGKKKD PNAPKRPPSA FFLFCSEHRP KIKSEHPGLS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 87%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 80%

Attributs du produit: This is a rabbit polyclonal antibody against HMGB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human HMGB2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 209 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HMGB2

Antigène: HMGB2 (High Mobility Group Box 2 (HMGB2))

Autre désignation: HMGB2

Sujet: HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. HMGB2 was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HMG2
Protein Interaction Partner: PKNOX1, UBC, EED, YWHAG, PGD, LDHB, CKB, HMGA1, GZMK, GZMA, CSNK1A1, FN1, SCAF8, APP, TFAP4, CDK2, BKRF1, Cebpb, ELAVL1, HMGB1, CHAF1A, CREBBP, SET, PGR, POU3F1, PRKDC, TP53, RAG1, POU5F1, POU2F2, POU2F1, APEX1, AR, NR3C1,
Protein Size: 209

Poids moléculaire: 24 kDa

ID gène: 3148

NCBI Accession: NM_002129, NP_002120

UniProt: P26583

Pathways: Cellular Response to Molecule of Bacterial Origin