KDM4B anticorps (Middle Region)

N° du produit ABIN2787592

Cet anticorps anti-KDM4B Polyclonal Lapin (ABIN2787592) détecte spécifiquement KDM4B dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Cheval, Porc, Boeuf (Vache) et Cobaye.

Aperçu rapide pour KDM4B anticorps (Middle Region) (ABIN2787592)

Antigène: KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Porc, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM4B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KDM4B anticorps

Épitope: Middle Region

Fonction: JMJD2B Antibody - middle region

Séquence: SASRASLKAK LLRRSHRKRS QPKKPKPEDP KFPGEGTAGA ALLEEAGGSV

Homologie: Cow: 92%, Dog: 93%, Guinea Pig: 83%, Horse: 93%, Human: 100%, Mouse: 82%, Pig: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against JMJD2B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human JMJD2B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58207-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur KDM4B

Antigène: KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

Autre désignation: JMJD2B

Sujet:

Background Information: JMJD2 family proteins are classified into one group with JD2H and TUDOR domains and another group without JD2H or TUDOR domains. Because JMJD2C gene (also known as GASC1 gene) is amplified in esophageal squamous cell carcinoma (ESCC), JMJD2 family genes are cancer-associated genes. Human genes corresponding to KIAA0677, KIAA0876, KIAA0780 and FLJ10251 cDNAs were designated JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively. In addition, JMJD2D homologous genes within human genome sequences AP002383.3 and AP001264.4 were designated JMJD2E and JMJD2F, respectively. C2HC2HC2- and C5HC2-type Cys (His) clusters were identified as the region conserved among JMJD2A (1064 aa), JMJD2B (1096 aa), and JMJD2C (1056 aa) proteins. JMJD2A, JMJD2B and JMJD2C consist of JmjN, JmjC, JD2H, and two TUDOR domains.

Gene Name: Lysine (K)-specific demethylase 4B

Alternative Symbols: JMJD2B, TDRD14B

Protein Name: Lysine-specific demethylase 4B

Poids moléculaire: 122kDa

ID gène: 23030

NCBI Accession: NP_055830

UniProt: O94953

Pathways: L'effet Warburg