USP22 anticorps (N-Term)

N° du produit ABIN2787646

Détail du produit anti-USP22 anticorps

Antigène: USP22 (Ubiquitin Specific Peptidase 22 (USP22))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Cheval, Chien, Cobaye, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP22 est non-conjugé

Application: Western Blotting (WB)

Séquence: RLHSCLYCVF FGCFTKKHIH EHAKAKRHNL AIDLMYGGIY CFLCQDYIYD

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against USP22. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human USP22

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 525 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur USP22

Antigène: USP22 (Ubiquitin Specific Peptidase 22 (USP22))

Autre désignation: USP22 (USP22 Produits)

Synonymes: anticorps USP3L, anticorps AI427806, anticorps zgc:136342, anticorps usp22, anticorps usp22 b, anticorps usp22-B, anticorps usp22-a, anticorps usp3l, anticorps ubiquitin specific peptidase 22, anticorps ubiquitin specific peptidase 22 S homeolog, anticorps USP22, anticorps Usp22, anticorps usp22, anticorps usp22.S

Sujet: USP22 is a subunit of the SAGA transcriptional cofactor complex. It deubiquitylates histone H2B and is recruited to specific genes by activators like Myc. USP22 is needed for cell cycle progression. It deubiquitylates histone H2A in addition to H2B. Altered mRNA expression is associated with therapy failure and death in patients multiple types of cancer.
Alias Symbols: KIAA1063, USP3L
Protein Interaction Partner: UBC, AASDHPPT, STAT3, TAF10, TADA2A, ATXN7, MYC, KAT2A, TRRAP, TAF9B, HIST1H2BD, TADA3, SUMO1, NFATC2, SIRT1, ATXN7L3, FUBP1, HIST2H2BE, HIST2H2AC, MRPL44, ATXN7L3B, USP27X, KIF7, KLHL23, ATXN7L2, TADA1, CCDC101, TADA2B, ENY2, SUPT20H, TAF5L, SND1, CNOT10
Protein Size: 525

Poids moléculaire: 60 kDa

ID gène: 23326

NCBI Accession: NM_015276, NP_056091

UniProt: Q9UPT9