CCR2 anticorps (C-Term)

N° du produit ABIN2787667

Détail du produit anti-CCR2 anticorps

Antigène: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Épitope: C-Term

Reactivité: Humain, Chien, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR2 est non-conjugé

Application: Western Blotting (WB)

Séquence: FTIMIVYFLF WTPYNIVILL NTFQEFFGLS NCESTSQLDQ ATQVTETLGM

Homologie: Cow: 79%, Dog: 79%, Horse: 79%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CCR2. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 374 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CCR2 (ABIN2787667)

Toka, Dunaway, Smaltz, Szulc-Dąbrowska, Drnevich, Mielcarska, Bossowska-Nowicka, Schweizer: "Bacterial and viral pathogen-associated molecular patterns induce divergent early transcriptomic landscapes in a bovine macrophage cell line." dans: BMC genomics, Vol. 20, Issue 1, pp. 15, (2019) (PubMed).

Murakami, Maeda, Yonezawa, Matsuki: "CC chemokine ligand 2 and CXC chemokine ligand 8 as neutrophil chemoattractant factors in canine idiopathic polyarthritis." dans: Veterinary immunology and immunopathology, Vol. 182, pp. 52-58, (2016) (PubMed).

Détails sur CCR2

Antigène: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Autre désignation: CCR2 (CCR2 Produits)

Synonymes: anticorps CC-CKR-2, anticorps CCR-2, anticorps CCR2A, anticorps CCR2B, anticorps CD192, anticorps CKR2, anticorps CKR2A, anticorps CKR2B, anticorps CMKBR2, anticorps MCP-1-R, anticorps ACKR5, anticorps CKRX, anticorps CRAM, anticorps CRAM-A, anticorps CRAM-B, anticorps HCR, anticorps Cc-ckr-2, anticorps Ccr2a, anticorps Ccr2b, anticorps Ckr2, anticorps Ckr2a, anticorps Ckr2b, anticorps Cmkbr2, anticorps mJe-r, anticorps C-C motif chemokine receptor 2, anticorps C-C motif chemokine receptor like 2, anticorps chemokine (C-C motif) receptor 2, anticorps CCR2, anticorps CCRL2, anticorps Ccr2, anticorps LOC484790

Sujet: This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase.
Alias Symbols: CKR2, CCR-2, CCR2A, CCR2B, CD192, CKR2A, CKR2B, CMKBR2, MCP-1-R, CC-CKR-2
Protein Size: 374

Poids moléculaire: 42 kDa

ID gène: 1231

NCBI Accession: NM_000647, NP_000638

UniProt: P41597

Pathways: cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process