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Glucose-6-Phosphate Dehydrogenase anticorps (Middle Region)

Cet anticorps anti-Glucose-6-Phosphate Dehydrogenase est un anticorps Lapin Polyclonal détectant Glucose-6-Phosphate Dehydrogenase dans WB. Adapté pour Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin et Mouton.
N° du produit ABIN2787697

Aperçu rapide pour Glucose-6-Phosphate Dehydrogenase anticorps (Middle Region) (ABIN2787697)

Antigène

Voir toutes Glucose-6-Phosphate Dehydrogenase (G6PD) Anticorps
Glucose-6-Phosphate Dehydrogenase (G6PD)

Reactivité

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Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Mouton

Hôte

  • 115
  • 15
  • 12
Lapin

Clonalité

  • 118
  • 24
Polyclonal

Conjugué

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Cet anticorp Glucose-6-Phosphate Dehydrogenase est non-conjugé

Application

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Western Blotting (WB)
  • Épitope

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    Middle Region

    Séquence

    VTKNIHESCM SQIGWNRIIV EKPFGRDLQS SDRLSNHISS LFREDQIYRI

    Homologie

    Cow: 85%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%, Sheep: 83%

    Attributs du produit

    This is a rabbit polyclonal antibody against G6PD. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the middle region of human G6PD
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 515 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    Glucose-6-Phosphate Dehydrogenase (G6PD)

    Autre désignation

    G6PD

    Sujet

    G6PD is a glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: G6PD1
    Protein Interaction Partner: G6PD, SUMO2, UBC, MDM2, CKB, CAPN1, ALDH7A1, ZNF622, ZFYVE19, UBFD1, CNDP2, ISOC1, MAT2B, ERP44, YWHAQ, SLC9A3R1, YWHAZ, YWHAH, YWHAG, YWHAE, YWHAB, EIF4H, VCL, UBE2V1, TGM2, PPP1R2, PGD, PAK2, LDHB, SFN, GNS, GLA, GBP2, EIF5, BAG3, FN1, CCT4, HARS, SUMO4
    Protein Size: 515

    Poids moléculaire

    57 kDa

    ID gène

    2539

    NCBI Accession

    NM_000402, NP_000393

    UniProt

    P11413

    Pathways

    Regulation of Systemic Arterial Blood Pressure by Hormones
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