GLP2R anticorps (N-Term)

N° du produit ABIN2787698

Cet anticorps anti-GLP2R est un anticorps Lapin Polyclonal détectant GLP2R dans WB. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour GLP2R anticorps (N-Term) (ABIN2787698)

Antigène: GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLP2R est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GLP2R anticorps

Épitope: N-Term

Séquence: KLGSSRAGPG RGSAGLLPGV HELPMGIPAP WGTSPLSFHR KCSLWAPGRP

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GLP2R. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GLP2R

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 553 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-GLP2R (ABIN2787698)

Sams, Hastrup, Andersen, Thim: "Naturally occurring glucagon-like peptide-2 (GLP-2) receptors in human intestinal cell lines." dans: European journal of pharmacology, Vol. 532, Issue 1-2, pp. 18-23, (2006) (PubMed).

Détails sur GLP2R

Antigène: GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))

Autre désignation: GLP2R

Sujet: The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R).
Alias Symbols: -
Protein Interaction Partner: UBC, GCG, CALM1,
Protein Size: 553

Poids moléculaire: 61 kDa

ID gène: 9340

NCBI Accession: NM_004246, NP_004237

UniProt: O95838

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Feeding Behaviour