ERP44 anticorps (Middle Region)

N° du produit ABIN2787804

Détail du produit anti-ERP44 anticorps

Antigène: ERP44 (Endoplasmic Reticulum Protein 44 (ERP44))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cheval, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERP44 est non-conjugé

Application: Western Blotting (WB)

Séquence: LHREFHHGPD PTDTAPGEQA QDVASSPPES SFQKLAPSEY RYTLLRDRDE

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against TXNDC4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TXNDC4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 406 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ERP44

Antigène: ERP44 (Endoplasmic Reticulum Protein 44 (ERP44))

Autre désignation: TXNDC4 (ERP44 Produits)

Synonymes: anticorps PDIA10, anticorps TXNDC4, anticorps 1110001E24Rik, anticorps AI849526, anticorps AL033348, anticorps Txndc4, anticorps BWK4, anticorps txndc4, anticorps zgc:77883, anticorps endoplasmic reticulum protein 44, anticorps ERP44, anticorps Erp44, anticorps erp44

Sujet: TXNDC4 mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. TXNDC4 inhibits the calcium channel activity of ITPR1. TXNDC4 may have a role in the control of oxidative protein folding in the endoplasmic reticulum. TXNDC4 is required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
Alias Symbols: ERP44, KIAA0573, PDIA10, TXNDC4
Protein Interaction Partner: FUS, UBC, SUMO1, NEDD8, NUDCD1, UBFD1, OSGEP, LARS, ISOC1, PLD3, PDCD10, FERMT2, YWHAZ, VCL, PFAS, PAK2, G6PD, FHL2, CNN2, TBCB, CKB, env, ELAVL1, SUMO4, RASSF5, USP32, USP46, UIMC1, ERO1LB, ERO1L, ITPR1, CD40,
Protein Size: 406

Poids moléculaire: 45 kDa

ID gène: 23071

NCBI Accession: NM_015051, NP_055866

UniProt: Q9BS26

Pathways: Cell RedoxHomeostasis, SARS-CoV-2 Protein Interactome