BNIP3L/NIX anticorps (Middle Region)

N° du produit ABIN2787863

L’anticorps anti-BNIP3L/NIX Polyclonal Lapin est utilisé pour la détection de BNIP3L/NIX dans des échantillons de Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Porc et Lapin. Il a été validé pour WB.

Aperçu rapide pour BNIP3L/NIX anticorps (Middle Region) (ABIN2787863)

Antigène: BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BNIP3L/NIX est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BNIP3L/NIX anticorps

Épitope: Middle Region

Fonction: Bnip3l Antibody - middle region

Séquence: CDSPSPQEDG QIMFDVEMHT SRDHSSQSEE EVVEGEKEVE ALKKSADWVS

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Bnip3l. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58878-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur BNIP3L/NIX

Antigène: BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

Autre désignation: Bnip3l

Sujet:

Background Information: Bnip3l induces apoptosis. It interacts with viral and cellular anti-apoptosis proteins. It can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. It inhibits apoptosis induced by BNIP3. It is involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. Bnip3l may function as a tumor suppressor.

Gene Name: BCL2/adenovirus E1B interacting protein 3-like

Alternative Symbols: N, Nix, Nip3L, C86132, D14Ertd719, D14Ertd719e

Protein Name: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

Poids moléculaire: 24kDa

ID gène: 12177

NCBI Accession: NP_033891

UniProt: Q9Z2F7

Pathways: Autophagy