BNIP3L/NIX anticorps (Middle Region)
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- Antigène Voir toutes BNIP3L/NIX (BNIP3L) Anticorps
- BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Lapin, Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BNIP3L/NIX est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- CDSPSPQEDG QIMFDVEMHT SRDHSSQSEE EVVEGEKEVE ALKKSADWVS
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against Bnip3l. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product BNIP3L Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 218 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
- Autre désignation
- Bnip3l (BNIP3L Produits)
- Synonymes
- anticorps BNIP3a, anticorps NIX, anticorps NIP3, anticorps Nix, anticorps Nip3, anticorps C86132, anticorps D14Ertd719e, anticorps Nip3L, anticorps bnip3l, anticorps nip3, anticorps zgc:110478, anticorps bnip3l2, anticorps wu:fb52b03, anticorps wu:fc02h04, anticorps BCL2 interacting protein 3 like, anticorps BCL2 interacting protein 3, anticorps BCL2/adenovirus E1B interacting protein 3, anticorps BCL2/adenovirus E1B interacting protein 3-like, anticorps BCL2/adenovirus E1B interacting protein 3-like b, anticorps BCL2/adenovirus E1B interacting protein 3-like a, anticorps BNIP3L, anticorps BNIP3, anticorps Bnip3l, anticorps Bnip3, anticorps bnip3lb, anticorps bnip3la
- Sujet
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Bnip3l induces apoptosis. It interacts with viral and cellular anti-apoptosis proteins. It can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. It inhibits apoptosis induced by BNIP3. It is involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. Bnip3l may function as a tumor suppressor.
Alias Symbols: C86132, D14Ertd719e, Nip3L, Nix
Protein Size: 218 - Poids moléculaire
- 24 kDa
- ID gène
- 12177
- NCBI Accession
- NM_009761, NP_033891
- UniProt
- Q9Z2F7
- Pathways
- Autophagy
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