Caspase 7 anticorps (N-Term)
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- Antigène Voir toutes Caspase 7 (CASP7) Anticorps
- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Porc, Chien, Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio), Boeuf (Vache), Chévre
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Caspase 7 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- NNKNFDKVTG MGVRNGTDKD AEALFKCFRS LGFDVIVYND CSCAKMQDLL
- Homologie
- Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human CASP7
- Top Product
- Discover our top product CASP7 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 336 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
- Autre désignation
- CASP7 (CASP7 Produits)
- Synonymes
- anticorps xCaspase-7, anticorps caspase-7, anticorps caspase7, anticorps cmh-1, anticorps ice-lap3, anticorps mch3, anticorps CASP7, anticorps AI314680, anticorps CMH-1, anticorps ICE-IAP3, anticorps Mch3, anticorps mCASP-7, anticorps CASP-7, anticorps ICE-LAP3, anticorps LICE2, anticorps MCH3, anticorps Caspase-7, anticorps MCH3/SCA-2, anticorps SCA-2, anticorps caspase 7, anticorps caspase-7, anticorps caspase 7 S homeolog, anticorps CASP7, anticorps xcaspase-7, anticorps casp7, anticorps casp7.S, anticorps Casp7
- Sujet
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This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.
Alias Symbols: CMH-1, ICE-LAP3, MCH3
Protein Interaction Partner: PTGES3, BAX, PARP1, SAT1, CRYAB, XIAP, RPS6KA1, CTSA, PEPD, MVD, GNS, GBP2, EEF2, CAPN1, CNDP2, GINS2, EIF4H, GZMB, ROCK1, DFFA, CASP9, CASP7, CASP3, ARHGDIA, VIM, STAT1, SPTAN1, CLSPN, PLA2G4B, RB1, UBC, BIRC2, CCT2, VCP, SP1, BIRC3, BIRC6, COPS6, TERF1,
Protein Size: 336 - Poids moléculaire
- 37 kDa
- ID gène
- 840
- NCBI Accession
- NM_033338, NP_203124
- UniProt
- P55210
- Pathways
- Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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