Caspase 7 anticorps (AA 24-303)

N° du produit ABIN3022072

Cité dans 1 publication. Cet anticorps anti-Caspase 7 Polyclonal Lapin (ABIN3022072) détecte spécifiquement Caspase 7 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Caspase 7 anticorps (AA 24-303) (ABIN3022072)

Antigène: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Caspase 7 anticorps

Épitope: AA 24-303

Séquence: AKPDRSSFVP SLFSKKKKNV TMRSIKTTRD RVPTYQYNMN FEKLGKCIII NNKNFDKVTG MGVRNGTDKD AEALFKCFRS LGFDVIVYND CSCAKMQDLL KKASEEDHTN AACFACILLS HGEENVIYGK DGVTPIKDLT AHFRGDRCKT LLEKPKLFFI QACRGTELDD GIQADSGPIN DTDANPRYKI PVEADFLFAY STVPGYYSWR SPGRGSWFVQ ALCSILEEHG KDLEIMQILT RVNDRVARHF ESQSDDPHFH EKKQIPCVVS MLTKELYFSQ

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 24-303 of human Caspase-7 (NP_001218.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-Caspase 7 (ABIN3022072)

Wu, Xiong, Li, Yang, Ge et al.: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." dans: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).

Détails sur Caspase 7

Antigène: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Autre désignation: Casp7

Sujet: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,CASP7,CASP-7,CMH-1,ICE-LAP3,LICE2,MCH3,caspase-7,Casp7,Cancer,Invasion and Metastasis,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Caspases,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases,Casp7

Poids moléculaire: 28 kDa/31 kDa/34 kDa/37 kDa

ID gène: 840

UniProt: P55210

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity