Caspase 10 anticorps (Middle Region)

N° du produit ABIN567450

Cet anticorps anti-Caspase 10 Polyclonal Lapin (ABIN567450) détecte spécifiquement Caspase 10 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Caspase 10 anticorps (Middle Region) (ABIN567450)

Antigène: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 10 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Caspase 10 anticorps

Épitope: Middle Region

Séquence: HNNVTKVEME MVLQKQKCNP AHADGDCFVF CILTHGRFGA VYSSDEALIP

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CASP10. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CASP10

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 479 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Caspase 10

Antigène: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Autre désignation: CASP10

Sujet: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: ALPS2, FLICE2, MCH4
Protein Interaction Partner: FADD, PRDX6, XIAP, RB1, Dlg4, PHF20L1, OIP5, ECE2, RIOK3, NFKBIL1, CASP8, RNF34, BFAR, CASP8AP2, MSN2, PTC2, AIM9, GLN3, SLT2, GPA1, STE20, ATG13, RPL21B, VPS30, CUP9, TPK2, GAL4, FAR11, WHI3, ATG4, FAR3, FAR8, ITT1, MPH1, SSM4, ASG1, BFR1, ORT1, MBR1, CW
Protein Size: 479

Poids moléculaire: 12 kDa

ID gène: 843

NCBI Accession: NM_001230, NP_001221

UniProt: Q92851

Pathways: Apoptose, Caspase Cascade in Apoptosis