TLR8 anticorps (C-Term)

N° du produit ABIN2787921

Cet anticorps anti-TLR8 Polyclonal Lapin (ABIN2787921) détecte spécifiquement TLR8 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Chévre, Cobaye, Cheval, Mouton et Lapin.

Aperçu rapide pour TLR8 anticorps (C-Term) (ABIN2787921)

Antigène: TLR8 (Toll-Like Receptor 8 (TLR8))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Chévre, Cobaye, Cheval, Mouton, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TLR8 anticorps

Épitope: C-Term

Fonction: TLR8 Antibody - C-terminal region

Séquence: LEPVLQHSQY LRLRQRICKS SILQWPDNPK AEGLFWQTLR NVVLTENDSR

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TLR8. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human TLR8

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59048-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur TLR8

Antigène: TLR8 (Toll-Like Receptor 8 (TLR8))

Autre désignation: TLR8

Sujet:

Background Information: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.

Gene Name: Toll-like receptor 8

Alternative Symbols: CD288

Protein Name: Toll-like receptor 8

Poids moléculaire: 120kDa

ID gène: 51311

NCBI Accession: NP_619542

UniProt: Q9NR97

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades