ATG5 anticorps (Middle Region)

N° du produit ABIN2787927

Cet anticorps anti-ATG5 est un anticorps Lapin Polyclonal détectant ATG5 dans WB. Adapté pour Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Lapin, Cobaye, Cheval, Chien et Mouton.

Aperçu rapide pour ATG5 anticorps (Middle Region) (ABIN2787927)

Antigène: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Lapin, Cobaye, Cheval, Chien, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ATG5 anticorps

Épitope: Middle Region

Séquence: RFDQFWAINR KLMEYPAEEN GFRYIPFRIY QTTTERPFIQ KLFRPVAADG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against ATG5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ATG5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 275 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ATG5

Antigène: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Autre désignation: ATG5

Sujet: ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 may play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
Alias Symbols: APG5, APG5-LIKE, APG5L, ASP, hAPG5
Protein Interaction Partner: TEKT4, CCHCR1, WIPI2, KEAP1, VCP, MEOX2, FADD, ATG16L1, RB1CC1, EXOC4, ATG3, ATG12, CAV1, HTT, WDFY3, TAB3, TAB2, TECPR1, ELAVL1, UBC, SIRT1, TKT, MAP1LC3C, MAP1LC3B, ATG10, ATG5, IMPDH2,
Protein Size: 275

Poids moléculaire: 32 kDa

ID gène: 9474

NCBI Accession: NM_004849, NP_004840

UniProt: Q9H1Y0

Pathways: Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy