RORC anticorps (N-Term)

N° du produit ABIN2787955

Cet anticorps Lapin Polyclonal détecte spécifiquement RORC dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cheval, Chien, Cobaye, Lapin, Porc, Chévre, Mouton et Poisson zèbre (Danio rerio).

Aperçu rapide pour RORC anticorps (N-Term) (ABIN2787955)

Antigène: RORC (RAR-Related Orphan Receptor C (RORC))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Chien, Cobaye, Lapin, Porc, Chévre, Mouton, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RORC est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RORC anticorps

Épitope: N-Term

Fonction: RORC Antibody - N-terminal region

Séquence: KICGDKSSGI HYGVITCEGC KGFFRRSQRC NAAYSCTRQQ NCPIDRTSRN

Homologie: Cow: 86%, Dog: 79%, Goat: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 79%, Rat: 86%, Sheep: 79%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against RORC. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RORC

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59155-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur RORC

Antigène: RORC (RAR-Related Orphan Receptor C (RORC))

Autre désignation: RORC

Sujet:

Background Information: RORC encodes a protein which is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that RORC may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: RAR-related orphan receptor C

Alternative Symbols: TOR, RORG, RZRG, IMD42, NR1F3, RZR-GAMMA

Protein Name: cDNA FLJ40675 fis, clone THYMU2021714, highly similar to NUCLEAR RECEPTOR ROR-GAMMA EMBL BAG53561.1

Poids moléculaire: 56kDa

ID gène: 6097

NCBI Accession: NP_001001523

UniProt: P51449

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway