GPR172A anticorps (C-Term)

N° du produit ABIN2788146

Cet anticorps anti-GPR172A Polyclonal Lapin (ABIN2788146) détecte spécifiquement GPR172A dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Porc, Cheval, Cobaye, Chien et Boeuf (Vache).

Aperçu rapide pour GPR172A anticorps (C-Term) (ABIN2788146)

Antigène: GPR172A (G Protein-Coupled Receptor 172A (GPR172A))

Reactivité: Humain, Souris, Rat, Porc, Cheval, Cobaye, Chien, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPR172A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GPR172A anticorps

Épitope: C-Term

Fonction: SLC52A2 Antibody - C-terminal region

Séquence: SLPSVTTGGS GPELQLGSPG AEEEEKEEEE ALPLQEPPSQ AAGTIPGPDP

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 93%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against SLC52A1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of human SLC52A2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59638-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur GPR172A

Antigène: GPR172A (G Protein-Coupled Receptor 172A (GPR172A))

Autre désignation: SLC52A2

Sujet:

Background Information: This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia.

Gene Name: solute carrier family 52 (riboflavin transporter), member 2

Alternative Symbols: PAR1, RFT3, RFVT2, hRFT3, BVVLS2, GPCR41, GPR172A, D15Ertd747e

Protein Name: solute carrier family 52, riboflavin transporter, member 2

Poids moléculaire: 38kDa

ID gène: 79581

NCBI Accession: NP_001240744

UniProt: Q9HAB3

Pathways: Nuclear Receptor Transcription Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response