Calnexin anticorps (C-Term)
Aperçu rapide pour Calnexin anticorps (C-Term) (ABIN2788198)
Antigène
Voir toutes Calnexin (CANX) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- RPWLWVVYIL TVALPVFLVI LFCCSGKKQT SGMEYKKTDA PQPDVKEEEE
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against CANX. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human CANX
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 592 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Calnexin (CANX)
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Autre désignation
- CANX
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Sujet
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This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.
Alias Symbols: CNX, FLJ26570, IP90, P90
Protein Interaction Partner: ERLIN2, HUWE1, UBC, TRAF6, SUMO2, TOR1A, STAU1, MDM2, LGR4, WWOX, NPHS1, RPA3, RPA2, RPA1, SUZ12, RNF2, BMI1, FBXO6, PTGIR, ADRB2, PDIA3, CLN5, YIPF3, SMURF2, env, PGRMC1, BCAP31, UBL4A, SERPINA1, MTNR1A, CSNK2A1, ATF2, CFTR, VCP, PKD2, LDLR, ASGR1, KCNH2
Protein Size: 592 -
Poids moléculaire
- 65 kDa
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ID gène
- 821
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NCBI Accession
- NM_001746, NP_001737
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UniProt
- P27824
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Pathways
- Signalisation MAPK, Thyroid Hormone Synthesis
Antigène
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