CRY1 anticorps (N-Term)

N° du produit ABIN2788200

Détail du produit anti-CRY1 anticorps

Antigène: CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval, Mouton, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRY1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: KRFQTLISKM EPLEIPVETI TSEVIEKCTT PLSDDHDEKY GVPSLEELGF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against CRY1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CRY1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 586 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CRY1 (ABIN2788200)

Currie, Doherty, Sillar: "Deep-brain photoreception links luminance detection to motor output in Xenopus frog tadpoles." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 21, pp. 6053-8, (2016) (PubMed).

Détails sur CRY1

Antigène: CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))

Autre désignation: CRY1 (CRY1 Produits)

Synonymes: anticorps cry1-A, anticorps CRY1, anticorps cry2, anticorps phll1, anticorps xCRY1, anticorps PHLL1, anticorps AU020726, anticorps AU021000, anticorps Phll1, anticorps ATCRY1, anticorps BLU1, anticorps BLUE LIGHT UNINHIBITED 1, anticorps CRYPTOCHROME 1 APOPROTEIN (BLUE LIGHT PHOTORECEPTOR, anticorps ELONGATED HYPOCOTYL 4, anticorps HY4, anticorps OOP2, anticorps OUT OF PHASE 2, anticorps T3H13.14, anticorps T3H13_14, anticorps cryptochrome 1, anticorps cryptochrome circadian clock 1 L homeolog, anticorps cryptochrome circadian regulator 1, anticorps cryptochrome circadian clock 1, anticorps Cryptochrome-1, anticorps cryptochrome 1, anticorps cryptochrome 1 (photolyase-like), anticorps cry1.L, anticorps CRY1, anticorps cry1, anticorps siu50817b, anticorps Cry1

Sujet: CRY1 is the blue light-dependent regulator of the circadian feedback loop. CRY1 inhibits CLOCK NPAS2-ARNTL E box-mediated transcription. CRY1 acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. CRY1 has no photolyase activity. CRY1 is capable of translocating circadian clock core proteins such as PER proteins to the nucleus. CRY1 may inhibit CLOCK NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL.
Alias Symbols: PHLL1
Protein Interaction Partner: PER2, FBXL3, FBXL21, PLSCR1, BTRC, CUL1, SKP1, CSNK1E, LTBP4, UBC, SNRPD3, GRN, USP2, Timeless, Cry1, KRTAP4-12, PER3, MDFI, CBLB, ARNTL, PER1, TRAF2,
Protein Size: 586

Poids moléculaire: 64 kDa

ID gène: 1407

NCBI Accession: NM_004075, NP_004066

UniProt: Q16526

Pathways: Response to Water Deprivation, Proton Transport