GRK1 anticorps (Middle Region)
Aperçu rapide pour GRK1 anticorps (Middle Region) (ABIN2788207)
Antigène
Voir toutes GRK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- GRK1 Antibody - middle region
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Séquence
- NKELKHRIIS EPVKYPDKFS QASKDFCEAL LEKDPEKRLG FRDETCDKLR
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Homologie
- Cow: 92%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 79%, Rat: 93%, Zebrafish: 83%
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Attributs du produit
- This is a rabbit polyclonal antibody against GRK1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human GRK1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59777-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))
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Autre désignation
- GRK1
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Sujet
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Background Information: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2).
Gene Name: G protein-coupled receptor kinase 1
Alternative Symbols: RK, RHOK, GPRK1
Protein Name: Rhodopsin kinase
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Poids moléculaire
- 63kDa
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ID gène
- 6011
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NCBI Accession
- NP_002920
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UniProt
- Q15835
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
Antigène
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