BBS10 anticorps (C-Term)

N° du produit ABIN2788220

Cet anticorps anti-BBS10 Polyclonal Lapin (ABIN2788220) détecte spécifiquement BBS10 dans WB. L’anticorps est réactif avec des échantillons de Humain et Lapin.

Aperçu rapide pour BBS10 anticorps (C-Term) (ABIN2788220)

Antigène: BBS10 (Bardet-Biedl Syndrome 10 (BBS10))

Reactivité: Humain, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BBS10 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BBS10 anticorps

Épitope: C-Term

Fonction: BBS10 Antibody - C-terminal region

Séquence: SQTGLESVMG KYQLLTSVLQ CLTKILTIDM VITVKRHPQK VHNQDSEDEL

Homologie: Human: 100%, Rabbit: 86%

Attributs du produit: This is a rabbit polyclonal antibody against BBS10. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human BBS10

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59803-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur BBS10

Antigène: BBS10 (Bardet-Biedl Syndrome 10 (BBS10))

Autre désignation: BBS10

Sujet:

Background Information: This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes. Mutations in this gene cause Bardet-Biedl syndrome type 10.

Gene Name: Bardet-Biedl syndrome 10

Alternative Symbols: C12orf58

Protein Name: Bardet-Biedl syndrome 10 protein

Poids moléculaire: 81kDa

ID gène: 79738

NCBI Accession: NP_078961

UniProt: Q8TAM1