ADRA1B anticorps (C-Term)

N° du produit ABIN2788281

Cet anticorps Lapin Polyclonal détecte spécifiquement ADRA1B dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye et Lapin.

Aperçu rapide pour ADRA1B anticorps (C-Term) (ABIN2788281)

Antigène: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRA1B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ADRA1B anticorps

Épitope: C-Term

Fonction: ADRA1B Antibody - C-terminal region

Séquence: YRPWTRGGSL ERSQSRKDSL DDSGSCLSGS QRTLPSASPS PGYLGRGAPP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ADRA1B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ADRA1B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59960-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur ADRA1B

Antigène: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Autre désignation: ADRA1B

Sujet:

Background Information: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.

Gene Name: Adrenergic, alpha-1B-, receptor

Alternative Symbols: ADRA1, ALPHA1BAR

Protein Name: Alpha-1B adrenergic receptor

Poids moléculaire: 57kDa

ID gène: 147

NCBI Accession: NP_000670

UniProt: P35368

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process