ADRA1B anticorps (C-Term)

N° du produit ABIN2788281

Détail du produit anti-ADRA1B anticorps

Antigène: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRA1B est non-conjugé

Application: Western Blotting (WB)

Séquence: YRPWTRGGSL ERSQSRKDSL DDSGSCLSGS QRTLPSASPS PGYLGRGAPP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ADRA1B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ADRA1B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 520 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ADRA1B

Antigène: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Autre désignation: ADRA1B (ADRA1B Produits)

Synonymes: anticorps LOC100136712, anticorps [a]1b, anticorps ADRA1, anticorps ALPHA1BAR, anticorps RDC5, anticorps alpha-1B adrenoceptor, anticorps adrenoceptor alpha 1B, anticorps adrenergic receptor, alpha 1b, anticorps LOC100136712, anticorps ADRA1B, anticorps Adra1b

Sujet: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
Alias Symbols: ADRA1, ALPHA1BAR
Protein Interaction Partner: ALB, AP2M1, GNAQ, STAT1, SAG, PRKCA, NOS1, GNA11, EZR, ADRA1A, FLNC,
Protein Size: 520

Poids moléculaire: 57 kDa

ID gène: 147

NCBI Accession: NM_000679, NP_000670

UniProt: P35368

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process