alpha 1 Adrenergic Receptor anticorps (C-Term)
Aperçu rapide pour alpha 1 Adrenergic Receptor anticorps (C-Term) (ABIN2788283)
Antigène
Voir toutes alpha 1 Adrenergic Receptor (ADRA1A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- LKSGLKTDKS DSEQVTLRIH RKNAPAGGSG MASAKTKTHF SVRLLKFSRE
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against ADRA1A. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human ADRA1A
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- alpha 1 Adrenergic Receptor (ADRA1A) (Adrenoceptor alpha 1A (ADRA1A))
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Autre désignation
- ADRA1A
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Sujet
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Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.
Alias Symbols: ADRA1C, ADRA1L1, ALPHA1AAR
Protein Interaction Partner: PPP1R9B, RGS2, ABR, NOS1, CXCR1, CXCR2, BMP1, ADRA1B, ADRA1D, FLNC,
Protein Size: 370 -
Poids moléculaire
- 40 kDa
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ID gène
- 148
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NCBI Accession
- NM_033304, NP_150647
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Pathways
- AMPK Signaling
Antigène
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