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F2RL1 anticorps (C-Term)

F2RL1 Reactivité: Humain, Rat, Chien, Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2788314
  • Antigène Voir toutes F2RL1 Anticorps
    F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
    Épitope
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 35
    • 9
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Chien, Cobaye
    Hôte
    • 34
    • 6
    Lapin
    Clonalité
    • 32
    • 8
    Polyclonal
    Conjugué
    • 24
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp F2RL1 est non-conjugé
    Application
    • 19
    • 16
    • 13
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    Western Blotting (WB)
    Séquence
    VSHDFRDHAK NALLCRSVRT VKQMQVSLTS KKHSRKSSSY SSSSTTVKTS
    Homologie
    Dog: 93%, Guinea Pig: 86%, Human: 100%, Rat: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against F2RL1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product F2RL1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 397 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Yau, Liu, Fairlie: "Toward drugs for protease-activated receptor 2 (PAR2)." dans: Journal of medicinal chemistry, Vol. 56, Issue 19, pp. 7477-97, (2013) (PubMed).

  • Antigène
    F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
    Autre désignation
    F2RL1 (F2RL1 Produits)
    Synonymes
    anticorps par2, anticorps GPR11, anticorps PAR2, anticorps Gpcr11, anticorps PAR-2, anticorps Par2, anticorps Par-2, anticorps Proteinase-activated receptor 2, anticorps F2R like trypsin receptor 1, anticorps coagulation factor II (thrombin) receptor-like 1, anticorps par2, anticorps F2RL1, anticorps F2rl1
    Sujet
    Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83 % identical to the mouse receptor sequence.
    Alias Symbols: GPR11, PAR2
    Protein Interaction Partner: BIRC5, COPS5, UBC, Cbl, ST14, GPRASP1, PRTN3, F2, PLG, ELANE, CTSG, CAPN2, CAPN1,
    Protein Size: 397
    Poids moléculaire
    44 kDa
    ID gène
    2150
    NCBI Accession
    NM_005242, NP_005233
    UniProt
    P55085
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
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