Cadherin 5 anticorps (Middle Region)
Aperçu rapide pour Cadherin 5 anticorps (Middle Region) (ABIN2788335)
Antigène
Voir toutes Cadherin 5 (CDH5) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- SLFVEDPDEP QNRMTKYSIL RGDYQDAFTI ETNPAHNEGI IKPMKPLDYE
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against CDH5. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 784 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Cadherin 5 (CDH5)
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Autre désignation
- CDH5
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Sujet
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This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.
Alias Symbols: 7B4, CD144, FLJ17376
Protein Interaction Partner: CTNNB1, MYC, P2RX4, P2RX6, PARD6A, SMG1, PKP4, F2RL2, CTNND1, SHC1, VIM, KDR, SRC, EPHA2, PTPRB, PTPN11, JUP, FGA, DSP, CSK, CTNNA1, FGB,
Protein Size: 784 -
Poids moléculaire
- 83 kDa
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ID gène
- 1003
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NCBI Accession
- NM_001795, NP_001786
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UniProt
- P33151
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Pathways
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
Antigène
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