CD55 anticorps (Middle Region)

N° du produit ABIN2788355

L’anticorps anti-CD55 Polyclonal Lapin est utilisé pour la détection de CD55 dans des échantillons de Humain, Chien et Cheval. Il a été validé pour WB.

Aperçu rapide pour CD55 anticorps (Middle Region) (ABIN2788355)

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Reactivité: Humain, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD55 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD55 anticorps

Épitope: Middle Region

Fonction: CD55 Antibody - middle region

Séquence: PGYRREPSLS PKLTCLQNLK WSTAVEFCKK KSCPNPGEIR NGQIDVPGGI

Homologie: Dog: 79%, Horse: 79%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CD55. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CD55

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60155-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CD55

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Autre désignation: CD55

Sujet:

Background Information: This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF), binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels.

Gene Name: CD55 Molecule, decay accelerating factor for complement (Cromer blood group)

Alternative Symbols: CR, TC, DAF, CROM, CHAPLE

Protein Name: Complement decay-accelerating factor

Poids moléculaire: 41kDa

ID gène: 1604

NCBI Accession: NP_000565

UniProt: P08174

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity