CD55 anticorps (Middle Region)

N° du produit ABIN2788355

Détail du produit anti-CD55 anticorps

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Épitope: Middle Region

Reactivité: Humain, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD55 est non-conjugé

Application: Western Blotting (WB)

Séquence: PGYRREPSLS PKLTCLQNLK WSTAVEFCKK KSCPNPGEIR NGQIDVPGGI

Homologie: Dog: 79%, Horse: 79%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CD55. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CD55

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 381 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CD55

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Autre désignation: CD55 (CD55 Produits)

Synonymes: anticorps CR, anticorps CROM, anticorps DAF, anticorps TC, anticorps Daf, anticorps Daf-GPI, anticorps Daf1, anticorps GPI-DAF, anticorps CD55 molecule (Cromer blood group), anticorps CD55 molecule, decay accelerating factor for complement, anticorps CD55, anticorps Cd55

Sujet: This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF), binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels.
Alias Symbols: CR, CROM, DAF, TC
Protein Interaction Partner: UBC, NDUFB7, NDUFS7, TIMM50, INF2, SYNJ2BP, PTCD3, PTRH2, MRPL4, SLC25A24, RAB31, ZMPSTE24, PICALM, SLC12A4, SLC2A1, S100A10, MPV17, MAN2A1, GNAI3, ATP6V1E1, GPLD1, CD97, CD14, LCK, FYN, CD55, CR1,
Protein Size: 381

Poids moléculaire: 41 kDa

ID gène: 1604

NCBI Accession: NM_000574, NP_000565

UniProt: P08174

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity