MARCKS anticorps (C-Term)
Aperçu rapide pour MARCKS anticorps (C-Term) (ABIN2788405)
Antigène
Voir toutes MARCKS AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- KAAEEPSKVE EKKAEEAGAS AAACEAPSAA GPGAPPEQEA APAEEPAAAA
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Homologie
- Cow: 86%, Human: 100%, Pig: 79%, Rabbit: 86%, Rat: 77%, Yeast: 80%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against MARCKS. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human MARCKS
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 332 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))
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Autre désignation
- MARCKS
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Sujet
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The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
Alias Symbols: 80K-L, FLJ14368, FLJ90045, MACS, PKCSL, PRKCSL
Protein Interaction Partner: UBC, TUBGCP3, UBQLN2, RPA2, PRKACA, PARK2, PKN1, PRKCB, HCVgp1, ATF2, PRKCZ, HSP90AA1, HNRNPU, DFFB, DBN1, SPP1, CDK4, CDK2, CDK1, CCNE1, ELAVL1, EBNA-LP, Mapk13, TOB1, PRKCA, NMT1, CTSB, CALM3, CALM2,
Protein Size: 332 -
Poids moléculaire
- 31 kDa
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ID gène
- 4082
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NCBI Accession
- NM_002356, NP_002347
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UniProt
- P29966
Antigène
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