ST5 anticorps (Middle Region)

N° du produit ABIN2788427

Détail du produit anti-ST5 anticorps

Antigène: ST5 (Suppression of Tumorigenicity 5 (ST5))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Cobaye, Cheval, Lapin, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ST5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: VPKPKRTFEY EADKNPKSKP SNGLPPSPTP AAPPPLPSTP APPVTRRPKK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ST5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ST5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1137 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ST5

Antigène: ST5 (Suppression of Tumorigenicity 5 (ST5))

Autre désignation: ST5 (ST5 Produits)

Synonymes: anticorps zgc:91902, anticorps wu:fc11b09, anticorps si:ch211-208c6.1, anticorps ST5, anticorps DKFZp459D1230, anticorps hts1, anticorps p126, anticorps dennd2b, anticorps DENND2B, anticorps HTS1, anticorps 2010004M01Rik, anticorps 2610305K15Rik, anticorps suppression of tumorigenicity 5, anticorps st5, anticorps ST5, anticorps St5

Sujet: This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.
Alias Symbols: DENND2B, HTS1, MGC33090, p126
Protein Interaction Partner: SMAD2, UBC, ABL1, SFN,
Protein Size: 1137

Poids moléculaire: 126 kDa

ID gène: 6764

NCBI Accession: NM_005418, NP_005409

UniProt: P78524