IL-18 anticorps (C-Term)

N° du produit ABIN2788556

Détail du produit anti-IL-18 anticorps

Antigène: IL-18 (IL18) (Interleukin 18 (IL18))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-18 est non-conjugé

Application: Western Blotting (WB)

Séquence: IIFFQRSVPG HDNKMQFESS SYEGYFLACE KERDLFKLIL KKEDELGDRS

Homologie: Human: 100%, Mouse: 79%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against IL18. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human IL18

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 193 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IL-18

Antigène: IL-18 (IL18) (Interleukin 18 (IL18))

Autre désignation: IL18 (IL18 Produits)

Synonymes: anticorps Igif, anticorps Il-18, anticorps IL-18, anticorps IGIF, anticorps ChIL-18, anticorps IL-1g, anticorps IL1F4, anticorps IL18, anticorps interleukin 18, anticorps Il18, anticorps IL18

Sujet: The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.
Alias Symbols: IGIF, IL-18, IL-1g, IL1F4, MGC12320
Protein Interaction Partner: CASK, UBC, IL1RL2, IL18RAP, IL18R1, IL18BP, CASP4, CASP3, CASP1,
Protein Size: 193

Poids moléculaire: 18 kDa

ID gène: 3606

NCBI Accession: NM_001562, NP_001553

UniProt: Q14116

Pathways: Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome